Evaluation of Clinical Effect of Anti-Infection Treatment after Surgical for Acute Suppurative Appendicitis
Objective To investigate the clinical effect of anti-infection treatment after surgical for acute suppurative appendicitis.Methods A total of 80 patients with acute suppurative appendicitis admitted to the General Surgery De-partment of Zichuan District Traditional Chinese Medicine Hospital in Zibo City from January 2022 to March 2023 were non-randomly selected as the study objects.They were randomly divided into a control group and a study group using different treatment modalities,with 40 cases in each group.Both groups underwent laparoscopic appendectomy.The control group received broad-spectrum antibiotic treatment after surgery,while the study group received high sen-sitivity antibiotic treatment after surgery.The incidence of complications,inflammatory indicators,clinical indicators,and quality of life were compared between the two groups.Results The incidence of complications in the study group(5.00%)was lower than that in the control group(25.00%),and the difference was statistically significant(χ2=6.274,P<0.05).The study group had shorter antibiotic use time,time to get out of bed,and hospital stay than the control group,and the differences were statistically significant(all P<0.05).After treatment,the levels of C-reactive protein,tumor necrosis factor alpha,interleukin-6,and interleukin-8 in the study group were lower than those in the control group,the differences were statistically significant(all P<0.05).The scores of vitality,physical function,emotional function,and physiological function in the study group were higher than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion After laparoscopic surgery for acute suppurative appendicitis,patients giving high sensitivity antibiotics for anti infection treatment based on drug sensitivity tests has a significant effect on reducing postoperative inflammatory reactions,reducing time of antimicrobial use,and reducing the inci-dence of complications.It is beneficial for promoting postoperative recovery and improving the quality of life of pa-tients.
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