首页|蛋白琥珀酸铁口服溶液治疗妊娠期缺铁性贫血的临床有效性评估

蛋白琥珀酸铁口服溶液治疗妊娠期缺铁性贫血的临床有效性评估

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目的 评估蛋白琥珀酸铁口服溶液辅助治疗妊娠期缺铁性贫血患者的疗效.方法 非随机选取北京燕化医院2022年7月—2023年7月收治的妊娠期缺铁性贫血患者80例.按治疗方法将所有研究对象分为参考组、观察组,各40例.参考组采用维生素C片+琥珀酸亚铁片的口服治疗,观察组采用维生素C片+蛋白琥珀酸铁口服溶液的口服治疗.对两组的治疗效果、生化指标情况、铁代谢指标情况、不良反应情况进行比对.结果 观察组治疗总有效率(95.00%)比参考组(75.00%)高,差异有统计学意义(χ2=6.274,P<0.05).治疗1个月后两组血红蛋白、红细胞计数、红细胞平均体积、血清铁、血清铁蛋白、转铁蛋白饱和度水平均升高,且观察组相较参考组高,差异有统计学意义(P均<0.05).两组不良反应发生率对比,差异有统计学意义(P<0.05).结论 对妊娠期缺铁性贫血孕妇行补铁治疗时辅以蛋白琥珀酸铁口服溶液治疗可使患者血生化指标、铁代谢情况得以有效改善,有效性与安全性均较高.
Clinical Efficacy Evaluation of Protein Succinate Iron Oral Solution in the Treatment of Iron Deficiency Anemia During Pregnancy
Objective To evaluate the efficacy of protein succinate iron oral solution as an adjuvant therapy for pa-tients with iron deficiency anemia during pregnancy.Methods 80 pregnant women with iron deficiency anemia admit-ted to Beijing Yanhua Hospital from July 2022 to July 2023.All study subjects were divided by treatment methods,with 40 cases in the reference group and 40 cases in the observation group.The reference group received oral treat-ment with vitamin C tablets and ferrous succinate tablets,and observation group received oral treatment with vitamin C tablets and protein iron succinate oral solution.The treatment effects,biochemical indicators,iron metabolism indi-cators,and adverse reactions between the two groups were compared.Results The total effective rate of treatment in the observation group was 95.00%,higher than the reference group with 75.00%,the difference was statistically sig-nificant(χ2=6.274,P<0.05).The hemoglobin,red blood cell count,average red blood cell volume,serum iron,serum ferritin,and transferrin saturation levels in both groups increased after one month of treatment,and the observation group was higher than the reference group,the difference was statistically significant(all P<0.05).There was statisti-cally significant in comparison of adverse reaction rates between two groups(P<0.05).Conclusion When supplement-ing iron therapy for pregnant women with iron deficiency anemia during pregnancy,supplementing with oral protein succinate iron solution can effectively improve the patient's blood biochemical indicators and iron metabolism,with high effectiveness and safety,which can provide clinical reference.

Protein succinate iron oral solutionPregnancy periodIron deficiency anemiaValidity

徐丽丽、王秋翠

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北京燕化医院妇产科,北京 102500

蛋白琥珀酸铁口服溶液 妊娠期 缺铁性贫血 有效性

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(13)