首页|PCT、CRP及WBC水平检测在儿童呼吸系统感染疾病中的诊断价值

PCT、CRP及WBC水平检测在儿童呼吸系统感染疾病中的诊断价值

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目的 探究降钙素原(procalcitonin,PCT)、C反应蛋白(C-reactive Protein,CRP)和白细胞计数(white blood cell count,WBC)水平检测在儿童呼吸系统感染疾病中的诊断价值.方法 非随机选取2022年6月—2023年6月江苏省淮安市洪泽区人民医院收治的328例呼吸系统感染患儿作为研究组,并选取同期健康体检者328名作为对照组.比较两组血清PCT、CRP、WBC水平,比较三种指标的诊断效能.结果 研究组PCT、CRP、WBC水平高于对照组,差异有统计学意义(P均<0.05).PCT检出336例,CRP检出324例,WBC检出324例.血清PCT、CRP、WBC检测的检查敏感度分别为83.54%(274/328)、73.48%(241/328)、72.87%(239/328),特异度为81.10%(266/328)、74.70%(245/328)、74.09%(243/328),准确度为82.32%(540/656)、74.09%(486/656)、73.48%(482/656),血清PCT检查敏感度、特异度以及准确度高于CRP、WBC,差异有统计学意义(P均<0.05).结论 相比于CRP、WBC检测,PCT检测在儿童呼吸系统感染疾病诊断中,具有较高的敏感度、特异度及准确度.
The Diagnostic Value of PCT,CRP and WBC Levels in Respiratory Infec-tions in Children
Objective To explore the diagnostic value of procalcitonin(PCT),C-reactive Protein(CRP)and white blood cell count(WBC)in children with respiratory infections.Methods 328 children with respiratory infection admit-ted to Hongze District People's Hospital of Huai'an City,Jiangsu Province from June 2022 to June 2023 were non-randomly selected as the study group,and 328 healthy subjects were selected as the control group.The levels of serum PCT,CRP and WBC were compared between the two groups,and the diagnostic efficacy of the three indexes was com-pared.Results The levels of PCT,CRP and WBC in the study group were higher than those in the control group,and the differences were statistically significant(all P<0.05).PCT positive 274 cases,CRP positive 241 cases,WBC posi-tive 239 cases.The sensitivity of serum PCT,CRP and WBC were 83.54%(274/328),73.48%(241/328)and 72.87%(239/328),the specificity was 81.10%(266/328),74.70%(245/328)and 74.09%(243/328),and the accuracy was 82.32%(540/656),74.09%(486/656)and 73.48%(482/656),respectively.The sensitivity,specificity and accuracy of serum PCT were higher than those of CRP and WBC,and the differences were statistically significant(all P<0.05).Conclusion Compared with CRP and WBC,PCT has higher sensitivity,specificity and accuracy in the diagnosis of re-spiratory infections in children.

Serum procalcitoninC-reactive proteinWhite blood cell countRespiratory systemInfectious diseaseSensitivitySpecificityAccuracy

王兆清、荣艺伟、陈颖

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江苏省淮安市洪泽区人民医院检验科,江苏 淮安 223008

血清降钙素原 C反应蛋白 白细胞计数 呼吸系统 感染疾病 敏感度 特异度 准确度

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(14)