Exploring the Efficacy of Freeze-dried Intravenous Injection of Human Immunoglobulin Combined with Cefoperazone Sodium and Sulbactam So-dium for Injection in the Treatment of Neonatal Infectious Pneumonia
Objective To analyze the effect of freeze-dried intravenous infusion of human immunoglobulin plus cefo-perazone sodium and sulbactam sodium on neonatal infectious pneumonia.Methods From August 2022 to August 2023,48 newborns with infectious pneumonia in the neonatology department of Juye County People's Hospital were non-randomly selected as the study objects.According to different treatment methods,they were divided into refer-ence group and combination group,24 cases in each group.The reference group was treated with cefoperazone sodium and sulbactan sodium,and the combination group was treated with freeze-dried intravenous human immunoglobulin.The inflammatory factors,symptom disappearance time and curative effect were compared between the two groups.Results The levels of interleukin-6,procalcitonin and c-reactive protein in the combined group were lower than those in the reference group.The time of symptom disappearance was shorter than that of reference group,and the differ-ences were statistically significant(all P<0.05).The effective rate of combination group was 95.83%(23/24),which was higher than 75.00%(18/24)of reference group,and the difference was statistically significant(χ2=4.181,P<0.05).Conclusion The application of human immunoglobulin plus cefoperazone sodium and sulbactam sodium in neonates with infectious pneumonia can shorten the time of symptom elimination,reduce pulmonary inflammation,and have a high effective rate.
Freeze-dried intravenous injection of human immunoglobulinEffectivenessInfectious pneumoniaAdverse reactionsCefoperazone sodium and sulbactam sodium
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维普
