首页|益生菌对儿童特应性皮炎的临床疗效及免疫功能的影响

益生菌对儿童特应性皮炎的临床疗效及免疫功能的影响

扫码查看
目的 探讨益生菌用于儿童特应性皮炎(atopic dermatitis,AD)治疗的临床疗效及对患儿免疫功能的影响.方法 非随机选取2020年8月—2023年8月南京市高淳人民医院收治的84例AD患儿为研究对象,按治疗方法分组,对照组42例实施对症治疗,观察组42例予以益生菌治疗.比较两组临床疗效、免疫指标及炎症因子水平.结果 观察组总有效率为97.62%(41/42),高于对照组的80.95%(34/42),差异有统计学意义(χ2=4.480,P<0.05).观察组免疫指标及炎症因子水平优于对照组,差异有统计学意义(P均<0.05).结论 益生菌用于儿童AD治疗具有显著临床疗效,能够有效提高患儿免疫功能,减轻炎症反应.
Effect of Probiotics on Clinical Efficacy and Immune Function in Children with Atopic Dermatitis
Objective To analyze the effect of probiotic treatment on atopic dermatitis(AD)in children and its impact on immune function.Methods A total of 84 children with AD admitted to Nanjing Gaochun People's Hospital from August 2020 to August 2023 were non-randomly selected as the research objects.According to the treatment methods,42 cases in the control group were treated with symptomatic treatment,and 42 cases in the observation group were treated with probiotics.The clinical efficacy,immune indexes and inflammatory factors were compared between the two groups.Results The total effective rate of the observation group was 97.62%(41/42),higher than 80.95%(34/42)of the control group,and the difference was statistically significant(χ2=4.480,P<0.05).The immune indexes and in-flammatory factor levels of the observation group were better than those of the control group,and the difference was statistically significant(all P<0.05).Conclusion Probiotics have significant clinical efficacy in the treatment of chil-dren with AD,which can effectively improve the immune function of children and reduce inflammation.

Children atopic dermatitisProbioticsClinical effectImmune functionCytokine

张兰

展开 >

南京市高淳人民医院儿科,江苏 南京 211300

儿童特应性皮炎 益生菌 临床疗效 免疫功能 细胞因子

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(14)