Research Progress on Drug Resistance Mechanism and Detection Technol-ogy of Mycobacterium Tuberculosis
Tuberculosis is a chronic respiratory infectious disease caused by mycobacterium tuberculosis,which is very harmful to human health and life.In the process of treatment,with the widespread use of anti tuberculosis drugs and the long-term use of anti tuberculosis drugs by tuberculosis patients,drug-resistant strains have emerged and con-tinue to spread.In Africa and Asia,where tuberculosis is high,there are more than 10 million patients with multi drug resistant tuberculosis(MDR-TB),which has become the main source of infection of tuberculosis.The emergence of drug-resistant strains in MDR-TB patients will lead to more deaths of tuberculosis patients due to serious conditions.Therefore,understanding the drug resistance mechanism of MDR-TB and establishing accurate and reliable drug re-sistance detection technology are of great significance for guiding clinical rational drug use and effective treatment of tuberculosis.
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