首页|丁苯酞辅助阿替普酶静脉溶栓治疗急诊脑卒中的效果及对患者神经功能的影响

丁苯酞辅助阿替普酶静脉溶栓治疗急诊脑卒中的效果及对患者神经功能的影响

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目的 研究丁苯酞联合阿替普酶静脉溶栓治疗脑卒中患者的效果以及对其神经功能的影响.方法 回顾性选取2021年2月—2023年2月丰县中医医院急诊科接诊的86例脑卒中患者的临床资料,按照治疗方式的不同分为对照组和观察组.对照组(n=43)实施阿替普酶静脉溶栓治疗,观察组(n=43)在对照组基础上联合丁苯酞辅助治疗.比较两组患者美国国立卫生研究院卒中量表评分、FuglMeyer评分、日常生活能力评分、Berg平衡量表评分,治疗前后凝血功能指标,治疗前后血液流变学指标及临床治疗效率.结果 治疗后观察组患者的美国国立卫生研究院卒中量表、FuglMeyer评分、日常生活能力评分、Berg平衡量表评分、凝血功能指标、血液流变学指标均优于对照组,差异有统计学意义(P均<0.05);观察组治疗总有效率为95.35%(41/43)高于对照组81.40%(35/43),差异有统计学意义(χ2=4.074,P<0.05).结论 脑卒中患者通过丁苯酞辅助阿替普酶静脉溶栓治疗,可有效改善其神经功能,提高治疗效率.
Effect of Butylphthalein Assisted with Ateplase Intravenous Thrombolysis in Emergency Stroke and Its Impact on Neurological Function of Patients
Objective To study the effect of butylphthalein combined with alteplase intravenous thrombolytic therapy on cerebral apoplexy patients and its influence on their neurological function.Methods The clinical data of eighty-six stroke patients admitted to the emergency department of Fengxian Hospital of Traditional Chinese Medicine from Feb-ruary 2021 to February 2023 were retrospectively selected,and they were divided into control group and observation group according to different treatment methods.The control group(n=43)received intravenous thrombolytic therapy with alteplase,and the observation group(n=43)was combined with the adjuvant treatment with butyphthalein on the basis of the control group.National Institutes of Health stroke scale score,FuglMeyer score,daily living ability score,Berg balance scale score,and coagulation function index before and after treatment were compared between the two groups.Hemorheology index and clinical treatment efficiency before and after treatment.Results After treatment,Na-tional Institutes of Health stroke scale score,FuglMeyer score,daily living ability score,Berg balance scale score,co-agulation function index and hemorheology index of observation group were better than those of control group,and the differences were statistically significant(all P<0.05).The total effective rate of the observation group was 95.35% (41/43)higher than 81.40% (35/43)of the control group,the difference was statistically significant(χ2=4.074,P<0.05).Conclusion Intravenous thrombolytic therapy of alteplase assisted by butylphthalein can effectively improve the neuro-logical function of stroke patients,and it is worth popularizing.

ButylphthaleinAteplaseIntravenous thrombolysisStrokeNeurological function

王连波、张震

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丰县中医医院急诊科,江苏 徐州 221700

丁苯酞 阿替普酶 静脉溶栓 脑卒中 神经功能

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(15)