Therapeutic Effect of Sodium Bicarbonate Ringer's Solution and Com-pound Sodium Chloride Injection on Septic Shock
Objective To explore the therapeutic effect of sodium bicarbonate Ringer's and compound sodium chlo-ride injection in the treatment of septic shock.Methods The clinical data of seventy patients with septic shock re-ceived limited fluid resuscitation from August 2021 to October 2023 were retrospectively selected,and divided into two groups according to different treatment methods,the differences of lactate clearance and electrolyte balance be-tween the control group(n=35,compound sodium chloride injection)and the observation group(n=35,sodium bicar-bonate ringer solution)were compared.Results The values of lactic acid in the observation group at 1,3 and 6 hours after treatmentwere significantly lower than those in the control group,the differences were statistically significant(all P<0.05).The level of Cl-was(106.23±3.17)mmol/L after forty-eight hours of treatment,significantly lower than the control group(110.94±2.72)mmol/L,the difference was statistically significant(t=6.671,P<0.05).Conclusion So-dium Bicarbonate Ringer's solution can be used in the treatment of limited fluid resuscitation in septic shock.Com-pared with compound sodium chloride injection,it can effectively clear lactic acid,maintain water-electrolyte balance and prevent functional failure,promote rapid recovery of patients.
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