首页|老年慢性阻塞性肺疾病合并肺部感染患者采用盐酸氨溴索治疗的临床研究

老年慢性阻塞性肺疾病合并肺部感染患者采用盐酸氨溴索治疗的临床研究

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目的 研究老年慢性阻塞性肺疾病(简称慢阻肺)合并肺部感染患者采用盐酸氨溴索治疗的效果.方法 非随机选取2021年1月—2023年12月江苏省句容市人民医院收治的158例慢阻肺患者,按治疗方法分为两组,各79例.对照组采用硫酸特布他林片治疗,研究组联合盐酸氨溴索治疗.对比两组临床疗效、肺功能指标、症状消失时间、不良反应发生率.结果 观察组总有效率为98.73%(78/79),高于对照组的91.14%(72/79),差异有统计学意义(χ2=4.740,P<0.05).研究组肺功能指标水平高于对照组,症状消失时间短于对照组,差异有统计学意义(P均<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论 老年慢阻肺合并肺部感染患者采用盐酸氨溴索治疗的效果好,能改善肺功能,且具有较高的安全性.
Clinical Study of Elderly Patients with Chronic Obstructive Pulmonary Disease Combined with Pulmonary Infections Treated with Ambroxol Hy-drochloride
Objective To study the effect of treatment with ambroxol hydrochloride in elderly patients with chronic ob-structive pulmonary disease combined with lung infections.Methods One hundred and fifty-eight patients with chronic obstructive pulmonary disease admitted to Jurong People's Hospital of Jiangsu Province from January 2021 to December 2023 were selected non-randomly and divided into two groups of seventy-eight cases each according to treatment methods.The control group was treated with terbutaline sulfate tablets,and the study group was treated with combined ambroxol hydrochloride.Compared the clinical efficacy,lung function indexes,symptom disappearance time,and the incidence of adverse reactions between the two groups.Results The total effective rate of the observation group was 98.73% (78/79),which was higher than 91.14% (72/79)of the control group,and the difference was statisti-cally significant(χ2=4.740,P<0.05).The level of lung function indexes in the study group were higher than those in the control group,and the time of symptom disappearance were shorter than those in the control group,and the differ-ences were statistically significant(all P<0.05).There was no statistically significant difference in the incidence of ad-verse reactions between the two groups(P>0.05).Conclusion Elderly patients with chronic obstructive pulmonary dis-ease combined with lung infections are well treated with ambroxol hydrochloride,which improves lung function and has a high safety profile.

Chronic obstructive pulmonary diseasePulmonary infectionAmbroxol hydrochlorideTherapeutic effectLung function

王文佳、张超、沈叶伟

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江苏省句容市人民医院呼吸科,江苏 镇江 212400

江苏省句容市人民医院CT室,江苏 镇江 212400

慢性阻塞性肺疾病 肺部感染 盐酸氨溴索 疗效 肺功能

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(15)