Effects of Laparoscopic Transumbilical Hernia Repair on Postoperative Pain,Serum Pain Mediators and Inflammatory Indexes in Patients with In-guinal Hernia
Objective To investigate the effects of laparoscopic transumbilical hernia repair on postoperative pain,se-rum pain mediators and inflammatory markers in patients with inguinal hernia.Methods Retrospectively selecting clinical data of sixty-six patients with inguinal hernia admitted to the Third People's Hospital of Xiantao City,Hubei Province from January 2020 to January 2023,the patients were divided into a control group(undergoing traditional laparoscopic retroperitoneal inguinal hernia repair)and a study group(undergoing laparoscopic umbilical hernia re-pair)based on surgical procedures,with thirty-three cases in each group.Compare the intraoperative bleeding volume,surgical time,24-hour incision pain score,serum pain mediators,postoperative complications,and inflammatory indi-cators between two groups.Results The postoperative incision pain score and inflammatory factor levels in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).24 hours after surgery,the levels of serum prostaglandin E2(2.68±0.24)ng/mL,calcitonin gene-related peptide(170.46±14.13)ng/mL,substance P(160.12±17.26)ng/L,and neuropeptide Y(140.56±12.43)ng/L in the study group were all lower than those in the control group(3.56±0.43)ng/mL,(194.88±21.10)ng/mL,(208.43±22.87)ng/L,(168.56±15.43)ng/L,and the differences were statistically significant(t=10.266,5.483,6.686,8.118,all P<0.05).There was no statis-tically significant difference in the incidence of complications between the two groups(P>0.05).Conclusion Transum-bilical hernia repair surgery for inguinal hernia is less painful compared to traditional surgery,effectively reduces in-flammatory reactions,and has significant advantages in clinical application compared to traditional surgery.
Inguinal herniaTransumbilical herniorrhaphyPain mediatorsInflammatory indexOperation timeAmount of bleeding
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