Analysis of the Diagnostic Value of Immunoglobulin M Antibody,High-Sensitivity C-reactive Protein and Serum Amyloid a Test in Children With Mycoplasma Pneumoniae
Objective To observe the diagnostic value of the combined detection of pediatric Mycoplasma pneumoniae immunoglobulin M(IgM)with hypersensitive C-reactive protein(hs-CRP)and serum amyloid A(SAA).Methods A total of 110 children with mycoplasma pneumoniae pneumonia admitted to Yanzhou District People's Hospital from January 2022 to June 2023 and no healthy children in the same period were non-randomly selected.The children with mycoplasma pneumoniae pneumonia were selected as the observation group,and the healthy children with physical examination were selected as the reference group.The test results of mycoplasma pneumoniae IgM antibody,hs-CRP and SAA were compared between the two groups,and ROC curve was drawn to analyze the diagnostic efficacy of mycoplasma IgM antibody+hs-CRP and SAA+hs-CRP as well as the combined test.Results The levels of mycoplasma pneumoniae IgM antibody,hs-CRP and SAA in observation group were higher than those in reference group,and the differences were statistically significant(all P<0.05).In the ROC curve,the AUC value of the combined detection of the three components was 0.930,higher than the 0.885 and 0.835 values of IgM+hs-CRP and SAA+hs-CRP.The sensitivity and specificity of the combined detection of the three components were higher than those of IgM+hs-CRP and SAA+hs-CRP in the detection of mycoplasma pneumoniae in children,the differences were statistically significant(both P<0.05).Conclusion The combined detection of Mycoplasma pneumoniae IgM antibody+hs-CRP and SAA is valuable for pediatric patients with Mycoplasma pneumoniae,with high sensitivity and specificity.
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