首页|海曲泊帕治疗实体瘤化疗所致血小板减少症的效果分析

海曲泊帕治疗实体瘤化疗所致血小板减少症的效果分析

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目的 探讨实体瘤化疗所致血小板减少症患者使用海曲泊帕治疗的效果.方法 目的抽样法选取2022年1月—2023年1月莘县人民医院肿瘤科收治的50例实体瘤化疗所致血小板减少症患者为研究对象,按照治疗方法不同分为参照组和研究组,各25例.参照组使用注射用重组人白介素11治疗,研究组行海曲泊帕治疗,比较两组疗效、血小板计数、不良反应发生情况.结果 研究组治疗总有效率高于参照组,差异有统计学意义(P<0.05).治疗后,研究组血小板计数为(117.82±9.63)×109/L,高于参照组的(108.31±5.60)×109/L,差异有统计学意义(t=4.268,P<0.05).研究组不良反应总发生率低于对照组,差异有统计学意义(P<0.05).结论 海曲泊帕可以对实体瘤化疗所致血小板减少症起到积极作用,可提升血小板计数水平,稳定病患临床指标,不良反应影响较少,应用价值较高.
Analysis of the Thrombocytopenia Effect of Chemotherapy in the Treat-ment of Solid Tumors
Objective To explore the efficacy of using Herceptin to treat thrombocytopenia in patients with solid tumor chemotherapy.Methods Fifty patients with solid tumor chemotherapy-induced thrombocytopenia admitted to the On-cology Department of Shen County People's Hospital from January 2022 to January 2023 were selected as the research subjects by target sampling method.They are divided into a reference group and a study group according to different treatment methods,with twenty-five cases in each group.The reference group received recombinant human interleu-kin 11 for injection treatment,while the study group received treatment with Herceptin.The efficacy,platelet count,and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the study group was higher than that of the reference group,and the difference was statistically significant(P<0.05).After treat-ment,the platelet count in the study group was(117.82±9.63)×109/L,which was higher than(108.31±5.60)×109/L in the reference group,and the difference was statistically significant(t=4.268,P<0.05).The total incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Haiqupopa can have a positive effect on thrombocytopenia caused by solid tumor chemotherapy,im-prove platelet count levels,stabilize clinical indicators of patients,have fewer adverse reactions,and have high appli-cation value.

Solid tumor chemotherapyThrombocytopeniaHaiqupapa

段秀芳、唐胜军、苑馨

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莘县人民医院肿瘤科,山东 聊城 252400

实体瘤化疗 血小板减少症 海曲泊帕

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(15)