首页|评价卡瑞利珠单抗联合安罗替尼三线治疗晚期非小细胞肺癌的效果

评价卡瑞利珠单抗联合安罗替尼三线治疗晚期非小细胞肺癌的效果

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目的 评估卡瑞利珠单抗联合安罗替尼三线治疗在晚期非小细胞肺癌中的应用效果.方法 非随机选取2022年10月—2023年10月如东县人民医院收治的70例晚期非小细胞肺癌患者为研究对象,按治疗方式不同分为常规组(单药安罗替尼治疗)与联合组(卡瑞利珠单抗联合安罗替尼治疗),各35例,比较两组的客观缓解率、疾病控制率、不良反应发生率及生活质量.结果 两组的客观缓解率和疾病控制率比较,差异无统计学意义(P均>0.05).两组不良反应发生率比较,差异无统计学意义(P均>0.05).治疗后,联合组生活质量评分为(78.63±4.85)分,高于常规组的(71.36±6.98)分,差异有统计学意义(t=5.060,P<0.05).结论 晚期非小细胞肺癌在临床治疗中采用卡瑞利珠单抗治疗联合安罗替尼治疗的效果良好,可以提高患者的生活质量.
Therapeutic Efficacy of Camrelizumab Plus Anlotinib on Advanced Non-Small Cell Lung Cancer
Objective To evaluate the efficacy of camrelizumab in advanced non-small cell lung cancer in combina-tion with anlotinib.Methods A total of seventy cases of advanced non-small cell lung cancer admitted to Rudong County People's Hospital from October 2022 to October 2023 were non-randomly selected as the study objects.Ac-cording to different treatment methods,they were divided into conventional group(single drug anlotinib treatment)and combined group(carrilitzumab combined with anlotinib treatment),with thirty-five cases in each group.Objective re-mission rate,disease control rate,incidence of adverse reactions and quality of life were compared between the two groups.Results There was no significant difference in the objective remission rate and disease control rate between the two groups(both P>0.05).There was no significant difference in the incidence of adverse reactions between the two groups(all P>0.05).The score of quality of life in the combined group was 78.63±4.85,which was higher than 71.36±6.98 of the conventional group,and the difference was statistically significant(t=5.060,P<0.05).Conclusion In the clinical treatment of advanced non-small cell lung cancer,carrilizumab combined with anlotinib is effective and can improve the quality of life of patients.

Advanced non-small cell lung cancerCamrelizumabAnlotinibThird-line therapy

李鹏、唐海梅、周爱华

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如东县人民医院肿瘤科,江苏 如东 226400

晚期非小细胞肺癌 卡瑞利珠单抗 安罗替尼 三线治疗

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(15)