首页|单核细胞分布宽度、降钙素原、超敏C反应蛋白和白细胞介素6联合检测在脓毒症患者中的诊断价值

单核细胞分布宽度、降钙素原、超敏C反应蛋白和白细胞介素6联合检测在脓毒症患者中的诊断价值

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目的 分析单核细胞分布宽度(monocyte distribution width,MDW)、降钙素原(procalcitonin,PCT)、超敏C反应蛋白(hypersensitive C-reactive protein,hs-CPR)和白细胞介素6(interleukin 6,IL-6)联合检测在脓毒症患者中的诊断价值.方法 非随机选取2022年3月—2024年2月东海县人民医院收治的脓毒症患者52例,根据病情程度分轻度组26例、重度组26例,另选取同期26名健康体检者为对照组.比较3组受检者上述指标水平,并分析指标单一及联合检测的诊断价值.结果 3组PCT、IL-6、hs-CPR、MDW水平比较,差异有统计学意义(P均<0.05).联合检测的灵敏度为94.23%(49/52)、准确度为94.87%(74/78),高于PCT、IL-6、hs-CPR、MDW单一检测的71.15%(37/52)、76.92%(60/78)、69.23%(36/52)、74.36%(58/78)、67.31%(35/52)、74.36%(58/78)、65.38%(34/52)、70.51%(55/78),差异有统计学意义(χ2=13.425、16.169,P均<0.05).结论 单核细胞分布宽度、降钙素原、超敏C反应蛋白和白细胞介素 6联合检测在脓毒症患者中诊断效能较高.
Diagnostic Value of Combined Tests for Monocyte Distribution Width,Cal-citoninogen,Hypersensitive C-reactive Protein,and Interleukin 6 in Pa-tients with Sepsis
Objective The diagnostic value of combined detection of monocyte distribution width(MDW),procalcito-nin(PCT),hypersensitive C-reactive protein(hs-CPR)and interleukin 6(IL-6)in patients with sepsis was analyzed.Methods Fifty-two cases of sepsis patients admitted to Donghai County People's Hospital from March 2022 to Febru-ary 2024 were selected non-randomly,and twenty-six cases were divided into twenty-six cases in the mild group and twenty-six cases in the severe group according to the degree of the condition,and another twenty-six healthy medical check-ups were selected as the control group in the same period.Compared the levels of the above indicators among the 3 groups of examinees and analyzed the diagnostic value of single and combined testing of the indicators.Results The levels of PCT,IL-6,hs-CPR,and MDW were compared among the 3 groups,and the differences were statistically significant(all P<0.05).The sensitivity of combined detection was 94.23%(49/52)and the accuracy was 94.87%(74/78),which was higher than that of the single test of PCT,IL-6,hs-CPR,and MDW,which was 71.15%(37/52),76.92%(60/78),69.23%(36/52),74.36%(58/78),67.31%(35/52),74.36%(58/78),65.38%(34/52),and 70.51%(55/78),and the differences were statistically significant(χ2=13.425,16.169,both P<0.05).Conclusion The diagnostic ef-ficacy of combined monocyte distribution width,calcitoninogen,hypersensitive C-reactive protein,and interleukin 6 testing is high in patients with sepsis.

SepsisMonocyte distribution widthProcalcitoninHigh-sensitivity C-reactive ProteinInterleukin 6

胡明、赵雯、黄廷廷、王加平

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东海县人民医院检验科,江苏 东海 222300

脓毒症 单核细胞分布宽度 降钙素原 超敏C反应蛋白 白细胞介素6

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(16)