Comparison of the Effect of Standard Dose and Half Dose Tirofiban as an Adjuvant PCI Treatment for Acute ST-segment Elevation Myocardial In-farction
Objective To compare the efficacy of standard dose and half-dose tirofiban assisted percutaneous coro-nary intervention(PCI)on acute ST-segment elevation myocardial infarction.Methods Ninety-four patients with acute ST-segment elevation myocardial infarction admitted to Shanghe County People's Hospital in Jinan City from January 2022 to June 2023 were non-randomly selected as study subjects.According to the treatment method,they were divided into standard-dose group and half-dose group,with fotry-seven patients in each group,and the two groups were treated with standard-measurement and half-dose tirofiban for adjuvant PCI,respectively.Compared the myocardial reperfusion indexes,cardiac function indexes,and complications of the two groups.Results There were no statistically significant differences in myocardial reperfusion indexes between the two groups(all P>0.05).The levels of cardiac function indexes in the half-dose group were better than those in the standard-dose group,and the differ-ences were statistically significant(all P<0.05).The complication rate of the half-dose group was 4.26%(2/47),which was higher than 19.15%(9/47)in the standard-dose group,and the difference was statistically significant(χ2=5.045,P<0.05).Conclusion The application of tirofiban in PCI therapy can effectively alleviate myocardial reperfu-sion in patients with acute ST-segment elevation myocardial infarction,and half-dose tirofiban improves patients'car-diac function more effectively and effectively reduces the risk of bleeding adverse effects.
TirofibanPercutaneous coronary interventionAcute ST segment elevationMyocardial injuryMyocardial infarction
NETL
NSTL
万方数据
