Analysis of Therapeutic Effects of Fluid Resuscitation at Different Time Points on Patients with Severe Acute Pancreatitis
Objective To investigate the value of pancreatitis(SAP)characterized by fluid resuscitation at different time points.Methods The clinical data of eighty NSAP patients admitted to Siyang Hospital from March 2023 to March 2024 were retrospectively selected and divided into two groups according to the resuscitation time,with forty cases in each group.The early group received resuscitation treatment within 8 h of abdominal pain,and the late group received resuscitation treatment 12 h after abdominal pain.The clinical indicators,biochemical indicators and out-comes of the two groups were compared.Results Fasting and water deprivation,recovery of physical signs and hospi-talization time in the early group were shorter than those in the late group,and the differences were statistically signifi-cant(all P<0.05).Compared with the late group,the creatinine level in the early group was higher,amylase and C-reactive protein were lower,and the differences were statistically significant(all P<0.05).The rate of multiple organ failure in the early group was 0,lower than 15.00%(6/40)in the late group,mechanical ventilation rate was 0,lower than 15.00%(6/40)in the late group,ICU transfer rate was 2.50%(1/40),lower than 20.00%(8/40)in the late group,and the differences were statistically significant(χ2=4.504,4.504,4.507,all P<0.05).Conclusion Liquid resuscita-tion therapy within 8 h of abdominal pain and 1 h after resuscitation can save the life of patients with SAP,and treat-ment within 8 h of abdominal pain can reduce prognostic adverse events,correct biochemical and metabolic status,and shorten the hospitalization period.
Severe acute pancreatitisTransfer situationLiquid resuscitationBiochemical indicatorsDifferent time points
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