不同时机高压氧介入治疗颅脑外伤的疗效研究
Study on the Therapeutic Effect of Hyperbaric Oxygen Intervention at Dif-ferent Timing in the Treatment of Traumatic Brain Injury
韩振 1张本营 1杨超 1于华杰 1郑泽洲1
作者信息
- 1. 济南市章丘区人民医院急诊外科,山东 济南 250200
- 折叠
摘要
目的 探讨不同时机高压氧(hyperbaric oxygen,HBO)介入治疗颅脑外伤(traumatic brain injury,TBI)的疗效.方法 非随机选取2022年8月—2023年7月在济南市章丘区人民医院接受HBO治疗的TBI88例患者为研究对象,根据HBO介入治疗时间进行分组,每组44例.研究组患者在伤后8～15 d接受HBO治疗,对照组患者在伤后16～30 d接受HBO治疗.对比两组疗效、残疾评定量表(Disability Rating Scale,DRS)与改良Barthel指数量表(Modified Barthel Index,MBI)评分.结果 研究组治疗总有效率为95.45%(42/44),高于对照组的79.55%(35/44),差异有统计学意义(χ2=5.091,P<0.05).治疗前两组DRS、MBI对比,差异无统计学意义(P均>0.05);随访3个月时与对照组结果相比,研究组DRS评分更低,MBI评分更高,差异有统计学意义(P均<0.05).结论 TBI患者病情稳定后尽早实施HBO治疗能够有效提高临床疗效,降低病残程度,促进日常生活活动能力的恢复.
Abstract
Objective To explore the therapeutic effect of hyperbaric oxygen(HBO)intervention at different times in the treatment of traumatic brain injury(TBI).Methods A total of eighty-eight TBI patients who received HBO treat-ment in Zhangqiu District People's Hospital of Jinan City from August 2022 to July 2023 were non-randomly selected as the study objects,and grouped according to HBO interventional treatment time,with forty-four in each group.Pa-tients in the study group received HBO treatment 8-15 days after injury,and the control group received HBO treat-ment 16～30 days after injury.The efficacy,Disability Rating Scale(DRS)and Modified Barthel Index(MBI)scores of the two groups were compared.Results The total effective rate of the study group was 95.45%(42/44),which was higher than 79.55%(35/44)of the control group,the difference was statistically significant(χ2=5.091,P<0.05).There was no significant difference in DRS and MBI between the two groups before treatment(both P>0.05).Compared with the control group,DRS score of the study group was lower and MBI score was higher after 3 months of follow-up,and the differences were statistically significant(both P<0.05).Conclusion Early implementation of HBO treatment in TBI patients after their condition stabilizes can effectively improve clinical efficacy,reduce disability,and promote the recovery of daily living activities.
关键词
高压氧/介入/颅脑外伤Key words
High pressure oxygen/Intervention/Craniocerebral trauma引用本文复制引用
出版年
2024
NETL
NSTL
万方数据