首页|不同时机高压氧介入治疗颅脑外伤的疗效研究

不同时机高压氧介入治疗颅脑外伤的疗效研究

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目的 探讨不同时机高压氧(hyperbaric oxygen,HBO)介入治疗颅脑外伤(traumatic brain injury,TBI)的疗效.方法 非随机选取2022年8月—2023年7月在济南市章丘区人民医院接受HBO治疗的TBI88例患者为研究对象,根据HBO介入治疗时间进行分组,每组44例.研究组患者在伤后8~15 d接受HBO治疗,对照组患者在伤后16~30 d接受HBO治疗.对比两组疗效、残疾评定量表(Disability Rating Scale,DRS)与改良Barthel指数量表(Modified Barthel Index,MBI)评分.结果 研究组治疗总有效率为95.45%(42/44),高于对照组的79.55%(35/44),差异有统计学意义(χ2=5.091,P<0.05).治疗前两组DRS、MBI对比,差异无统计学意义(P均>0.05);随访3个月时与对照组结果相比,研究组DRS评分更低,MBI评分更高,差异有统计学意义(P均<0.05).结论 TBI患者病情稳定后尽早实施HBO治疗能够有效提高临床疗效,降低病残程度,促进日常生活活动能力的恢复.
Study on the Therapeutic Effect of Hyperbaric Oxygen Intervention at Dif-ferent Timing in the Treatment of Traumatic Brain Injury
Objective To explore the therapeutic effect of hyperbaric oxygen(HBO)intervention at different times in the treatment of traumatic brain injury(TBI).Methods A total of eighty-eight TBI patients who received HBO treat-ment in Zhangqiu District People's Hospital of Jinan City from August 2022 to July 2023 were non-randomly selected as the study objects,and grouped according to HBO interventional treatment time,with forty-four in each group.Pa-tients in the study group received HBO treatment 8-15 days after injury,and the control group received HBO treat-ment 16~30 days after injury.The efficacy,Disability Rating Scale(DRS)and Modified Barthel Index(MBI)scores of the two groups were compared.Results The total effective rate of the study group was 95.45%(42/44),which was higher than 79.55%(35/44)of the control group,the difference was statistically significant(χ2=5.091,P<0.05).There was no significant difference in DRS and MBI between the two groups before treatment(both P>0.05).Compared with the control group,DRS score of the study group was lower and MBI score was higher after 3 months of follow-up,and the differences were statistically significant(both P<0.05).Conclusion Early implementation of HBO treatment in TBI patients after their condition stabilizes can effectively improve clinical efficacy,reduce disability,and promote the recovery of daily living activities.

High pressure oxygenInterventionCraniocerebral trauma

韩振、张本营、杨超、于华杰、郑泽洲

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济南市章丘区人民医院急诊外科,山东 济南 250200

高压氧 介入 颅脑外伤

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(16)