首页|雌二醇片/雌二醇地屈孕酮片在女性围绝经期综合征患者中的应用

雌二醇片/雌二醇地屈孕酮片在女性围绝经期综合征患者中的应用

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目的 探讨雌二醇片/雌二醇地屈孕酮片在女性围绝经期综合征患者中的应用价值.方法 非随机选取2022年2月—2023年12月长沙市第四医院收治的围绝经期综合征患者80例为研究对象.按治疗方法分为两组,每组40例.对照组给予坤泰胶囊治疗,观察组给予雌二醇片/雌二醇地屈孕酮片治疗.比较两组性激素水平、性生活质量评分及临床症状改善时间.结果 观察组卵泡刺激素(33.5±3.5)U/L、黄体生成素水平(31.5±6.0)U/L低于对照组的(41.2±2.9)U/L、(37.1±2.9)U/L,雌二醇水平(25.6±3.1)mg/L高于对照组的(16.6±2.4)mg/L,差异有统计学意义(t=10.714、7.972、14.519,P均<0.05).观察组性生活质量评分高于对照组,临床症状改善时间短于对照组,差异有统计学意义(P均<0.05).结论 雌二醇片/雌二醇地屈孕酮片治疗女性围绝经期综合征,可有效维持机体性激素水平平衡,改善性生活质量,缓解不适症状.
Application of Estradiol Tablets/Estradiol Progesterone Tablets with Cli-macteric Syndrome
Objective To explore the application value of estradiol tablets/estradiol dydrogesterone tablets with peri-menopausal syndrome patients.Methods Eighty cases patients of menopausal syndromes admitted to Changsha Fourth Hospital from February 2022 to December 2023 were non-randomly selected as study subjects.They were divided into two groups according to the treatment method,with forty cases in each group.The control group was given kuntai capsule treatment,and the observation group was given estradiol tablets/estradiol dydrogesterone tablets treatment.Sex hormone level,sexual life quality score and clinical symptoms improvement time were compared between the two groups.Results The levels of follicle-stimulating hormone(33.5±3.5)U/L and luteinizing hormone(31.5±6.0)U/L in the observation group were lower than(41.2±2.9)U/L and(37.1±2.9)U/L in the control group,and the level of estra-diol(25.6±3.1)mg/L was higher than(16.6±2.4)mg/L in the control group,and the differences were statistically sig-nificant(t=10.714,7.972,14.519,all P<0.05).The observation group's sexual quality of life scores were higher than those of the control group,and the time to improve clinical symptoms were shorter than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion Estradiol tablets/estradiol dydrogesterone tablets can effectively maintain the balance of sex hormone levels,improve sexual therapy and relieve discomfort symptoms in the treatment of female climacteric syndrome.

Estradiol tabletsEstradiol dydrogesterone tabletsClimacteric syndrome

苏晴、谢诚芳、张阳

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长沙市第四医院妇产科,湖南 长沙 410203

雌二醇片 雌二醇地屈孕酮片 围绝经期综合征

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(16)