Objective To analyze the efficacy of fluoxetine in the treatment of elderly epilepsy patients with mild to moderate depression and its improvement effect on depression.Methods Eighty-eight elderly patients with mild to moderate depression caused by epilepsy admitted to Xintai Mental Hospital in Shandong Province from February 2022 to September 2023 were non-randomly selected as the research subjects.They were divided into an observation group and a control group according to different treatment methods,with forty-four cases in each group.Both groups of pa-tients received routine antiepileptic treatment,while the observation group received additional treatment with fluox-etine.Compare the treatment outcomes,depression scores,and incidence of adverse reactions between two groups of patients.Results The total effective rate of the observation group was 97.73% (43/44),which was higher than 81.82%(36/44)of the control group,and the difference was statistically significant(χ2=4.456,P<0.05).The Hamilton Depres-sion Rating Scale scores of the observation group were lower than those of the control group at 4,6,and 8 weeks of treatment,and the differences were statistically significant(all P<0.05).There was no statistically significant differ-ence in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The use of fluoxetine in the treatment of elderly patients with epilepsy and mild to moderate depression has definite advantages,as it can effec-tively improve the patient's disease symptoms without increasing adverse reactions.
关键词
氟西汀/老年癫痫/轻中度抑郁/抑郁评分
Key words
Fluoxetine/Elderly epilepsy/Mild to moderate depression/Depression score
维普
万方数据