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无抽搐电休克疗法对双相情感障碍患者的效果研究

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目的 针对双相情感障碍患者进行治疗时,探究采用无抽搐电休克疗法的临床疗效.方法 非随机选取2020年6月—2023年6月菏泽市第三人民医院精神科收治的100例双相情感障碍患者为研究对象,根据治疗方式不同分为药物治疗组和联合治疗组,各50例.药物治疗组使用富马酸喹硫平片单药治疗,联合治疗组使用富马酸喹硫平片联合应用无抽搐电休克疗法,对比两组治疗情况及不良反应发生率.结果 治疗前两组患者临床症状比较,差异无统计学意义(P均>0.05),治疗后两组症状均较治疗前改善,且联合治疗组优于药物治疗组,差异有统计学意义(P均<0.05);联合治疗组不良反应发生率为14.00%(7/50),略低于药物治疗组的12.00%(6/50),但差异无统计学意义(χ2=0.088,P>0.05).结论 在进行双相情感障碍治疗过程中,在药物治疗的基础上加用无抽搐电休克疗法,可以有效改善患者症状,且不会增加不良反应.
Effect of Non-convulsive Electroconvulsive Therapy in Patients with Bipo-lar Disorder
Objective To analyze the effectiveness of non convulsive electroconvulsive therapy in the treatment of pa-tients with bipolar disorder.Methods A total of 100 patients with bipolar disorder who came to the psychiatric depart-ment of Heze Third People's Hospital from June 2020 to June 2023 were non-randomly selected as the study objects and divided into drug treatment group and combined treatment group according to different treatment methods,with 50 cases in each group.The drug treatment group was treated with quetiapine fumarate tablet,and the combined treat-ment group was treated with quetiapine fumarate tablet,combined with non-convulsive electroconvulsive therapy.The scale scores and incidence of adverse reactions were compared between the two groups.Results Before treatment,there were no statistical significances in clinical symptoms scores between the two groups(all P>0.05).After treat-ment,the symptoms of the two groups were improved compared with those before treatment,and the combined treat-ment group was superior to the drug treatment group,the differences were statistically significant(all P<0.05).The in-cidence of adverse reactions in the combined treatment group was 14.00% (7/50),slightly lower than 12.00%(6/50)in the drug treatment group,but the difference was not statistically significant(χ2=0.088,P>0.05).Conclusion In the treatment of bipolar disorder,non-convulsive electroconvulsive therapy on the basis of drug therapy can effectively im-prove the condition of patients without increasing adverse reactions.

Non-convulsive electroconvulsive therapyBipolar disorderClinical efficacy

张杏、刘合英、万凤娇、宋茜

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菏泽市第三人民医院精神科,山东 菏泽 274000

菏泽市立医院,山东 菏泽 274000

无抽搐电休克疗法 双相情感障碍 临床效果

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(17)