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早期应用他汀类药物对脑梗死患者的治疗效果评价

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目的 研究脑梗死患者早期给予他汀类药物的疗效.方法 目的选取2022年10月—2023年10月潍坊市中医院收治的96例脑梗死患者为研究对象,按治疗方法不同分为两组,对照组采取常规治疗方案,观察组在前组基础上早期给予他汀类药物(阿托伐他汀),比较两组临床疗效、血脂指标和氧化炎症指标.结果 观察组的临床总疗效为95.83(46/48),高于对照组的83.33%(40/48),差异有统计学意义(χ2=4.018,P<0.05).治疗后,观察组总胆固醇、甘油三酯、低密度脂蛋白较对照组更低,高密度脂蛋白较对照组高,差异有统计学意义(P均<0.05).观察组氧化炎症指标均低于对照组,差异有统计学意义(P均<0.05).结论 脑梗死患者在常规治疗基础上早期给予他汀类药物治疗,可进一步改善血脂指标,降低机体氧化炎症反应,提高治疗效果,具有临床价值.
Evaluation of the Therapeutic Effect of Early Application of Statins on Pa-tients with Cerebral Infarction
Objective To study the efficacy of early administration of statins in patients with cerebral infarction.Methods Ninety-six patients with cerebral infarction admitted to Weifang Traditional Chinese Medicine Hospital from October 2022 to October 2023 were objectively selected as the study subjects.They were divided into two groups us-ing different treatment methods.The control group received routine treatment,while the observation group received early statin medication(atorvastatin)on basis of the previous group.The clinical efficacy,blood lipid indicators,and oxidative inflammation indicators between two groups were compared.Results The total clinical efficacy of the obser-vation group was 95.83% (46/48),higher than 83.33%(40/48)of the control group,the difference was statistically sig-nificant(χ2=4.018,P<0.05).After treatment,the observation group had lower total cholesterol,triglycerides,low-density lipoprotein and higher high-density lipoprotein than control group,the differences were statistically significant(all P<0.05).The oxidative inflammation indicators in the observation group were lower than those in the control group,the differences were statistically significant(all P<0.05).Conclusion Early administration of statins in patients with cerebral infarction on the basis of conventional treatment can further improve blood lipid indicators,reduce oxida-tive inflammatory reactions in the body,and improve treatment effectiveness,which has clinical value.

Cerebral infarctionEarly treatmentStatin drugsClinical efficacy

王远波、马晓艳、于德明

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潍坊市中医院,山东 潍坊 261000

脑梗死 早期治疗 他汀类药物 临床疗效

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(17)