Analysis of the Application Value of Combined Detection of Antibody and High-sensitivity C-reactive Protein in the Diagnosis of Mycoplasma Pneu-moniae Infection in Children
Objective To explore the application value of combined detection of antibody and hypersensitive C-reactive protein(hs-CRP)in the diagnosis of mycoplasma pneumoniae infection in children.Methods From January 2023 to April 2024,the clinical data of ninety children with mycoplasma pneumoniae infection admitted to Wuhai Mongolian Traditional Chinese Medicine Hospital were retrospectively selected as the infection group,and the clinical data of ninety healthy children in the same period were retrospectively selected as the healthy group.All children were tested for antibodies and hs-CRP,and the diagnostic efficacy and consistency of these two detection methods alone and in combination were compared and analyzed.Results The Kappa value of antibody detection alone was 0.722,and the kappa value of hs-CRP detection was 0.611,indicating that the consistency with clinical diagnosis was moderate.The kappa value of the combined detection was as high as 0.967,indicating a high consistency with the clinical diag-nosis results.In addition,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value of combined detection were significantly higher than those of single detection method(all P<0.05).Conclusion The combination of antibody and hs-CRP showed high diagnostic efficacy and consistency in the diagnosis of pediatric My-coplasma pneumoniae infection,which has more obvious advantages than the single detection method,and can provide a more accurate diagnostic basis for the clinic.
Children pneumonia mycoplasmaAntibodyHigh-sensitivity C-reactive proteinCombined detectionDiagnostic performance
万方数据
维普
