The Effect of High-throughput Hemodialysis Combined with Hemoperfu-sion and Recombinant Human Erythropoietin on the Microinflammatory Status in Hemodialysis Patients with Renal Anemia
Objective To probe into the effect of high-throughput hemodialysis tandem hemoperfusion combined with recombinant human erythropoietin on microinflammation in hemodialysis patients with renal anemia.Methods Sev-enty cases of renal anemia hemodialysis patients admitted to Xinhui District People's Hospital of Jiangmen City,Guangdong Province from March 2023 to March 2024 were objectively selected as the study subjects.According to dif-ferent treatment methods,they were divided into observation group and control group,with thirty five cases in each group.The control group was treated with high-flux hemodialysis combined with recombinant human erythropoietin,and the observation group was treated with high-flux hemodialysis combined with hemoperfusion combined with re-combinant human erythropoietin.The efficacy,anemia index,renal function index,inflammatory factor level and ad-verse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 100.00% (35/35),which was higher than 80.00%(28/35)in the control group,and the difference was statis-tically significant(χ2=5.714,P<0.05).After treatment,the anemia indexes of the observation group were higher than those of the control group,and the differences were statistically significant(all P<0.05).After treatment,the renal function indexes of the observation group were lower than those of the control group,and the differences were statisti-cally significant(all P<0.05).After treatment,the levels of inflammatory factors in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the observation group was higher than that in the control group,but the difference was not statistically sig-nificant(P>0.05).Conclusion High-flux hemodialysis combined with hemoperfusion combined with recombinant hu-man erythropoietin in the treatment of hemodialysis patients with renal anemia can improve the level of inflammation in patients,with good efficacy and high safety.
Renal anemia hemodialysisHigh throughput hemodialysis tandem hemoperfusionRecombinant human erythropoietin
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