Study on the Efficacy and Safety of Flexible Ureteroscope Versus Percuta-neous Nephrolithotomy in the Treatment of 2～3 cm Single Renal Calculi
Objective To compare and analyze the efficacy and safety of transurethral ureteroscopy and percutaneous nephrolithotomy in the treatment of 2～3 cm single renal calculi.Methods From June 2021 to June 2024,200 patients with 2～3 cm single renal calculi admitted to Heyuan People's Hospital were non-randomly selected as the research objects.According to different treatment methods,they were divided into two groups.120 patients treated with flexible ureteroscopy were RIRS group,and 80 patients treated with percutaneous nephrolithotomy were PCNL group.The sur-gical indexes,renal function indexes,serum indexes,pain conditions and incidence of complications were compared between the two groups.Results The operation time of RIRS group was longer than that of PCNL group,but the intra-operative blood loss,hospitalization time,hospitalization cost and hemoglobin decrease were lower than those of PCNL group,and the differences were statistically significant(all P<0.05).The one-stage stone clearance rate in the RIRS group was lower than that in the PCNL group,and the difference was statistically significant(P<0.05).After operation,urea nitrogen,serum creatinine,procalcitonin and white blood cell count in RIRS group were lower than those in PCNL group,and hemoglobin index in the RIRS group was higher than that in PCNL group,and the differences were statistically significant(all P<0.05).The pain scores of RIRS group were lower than those of PCNL group at 1 d and 2 d after operation,and the differences were statistically significant(both P<0.05).The incidence of complications in the RIRS group was 1.67% (2/120)lower than that in the PCNL group 13.75%(11/80),and the difference was statisti-cally significant(χ2=11.531,P<0.05).Conclusion In the treatment of patients with single renal calculi of 2～3 cm,RIRS and PCNL are safe and effective.RIRS has little damage to human body,rapid postoperative recovery,low inci-dence of complications and mild pain.The stone clearance rate of PCNL is high,and the operation time is short.The choice of operation method needs to be combined with the needs of patients and the condition of the disease.
Flexible ureteroscopePercutaneous nephroscopy2～3 cm single renal calculiEffectivenessSecurity
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