Early Warning Value of Serum AMH and Uterine Adnexal Ultrasound Pa-rameters in Fast Progressive Central Precocious Puberty in Girls
Objective To analyze the value of serum anti-Mullerian hormone(AMH)and adnexal B ultrasound param-eters in early warning of rapidly progressing central precocious puberty in girls.Methods Sixty cases of central preco-cious puberty(CPP)girls admitted to the North Guangdong People's Hospital of Shantou University Medical School from June 2022 to June 2024 were non-randomly selected as the study objects.According to the indicators of rapid progression,they were divided into slow progressive central precocious puberty(SP-CPP)group and fast progressive central precocious puberty(RP-CPP)group,with thirty cases each,and thirty healthy girls in the same period were se-lected as control group.All girls underwent serum AMH and uterine adnexal B ultrasound detection,and the clinical indicators and early warning value of the three groups of girls were statistically analyzed.Results Serum AMH(3.79±1.24)ng/mL and(2.63±0.31)ng/mL in SP-CPP group and RP-CPP group were lower than those in control group(5.30±1.50)ng/mL,and the difference was statistically significant(F=41.540,P<0.05).Serum AMH in RP-CPP group was lower than that in SP-CPP group,and the difference was statistically significant(P<0.05).There was no signifi-cant difference in transverse diameter between SP-CPP group and RP-CPP group(P>0.05).The longitudinal diam-eter,anteroposternal diameter and uterine volume of SP-CPP group were lower than those of RP-CPP group,and the differences were statistically significant(all P<0.05).The ultrasonic parameters of ovary in SP-CPP group and RP-CPP group were higher than those in control group,and the RP-CPP group were higher than SP-CPP group,the differ-ences were statistically significant(all P<0.05).The AUC for early warning of rapid progression of CPP in girls with uterine volume was 0.789.Conclusion AMH and uterine annex B ultrasound parameters have certain early warning value for girls with rapid progression of central precocious puberty,and uterine volume has the highest early warning value.
Central precocious puberty in girlsEarly warningSerum anti mullerian hormoneUltrasound parameters of uterine adnexa
万方数据
维普
