首页|B型钠尿肽联合心肌肌钙蛋白I在诊断急性心肌梗死患者中的价值研究

B型钠尿肽联合心肌肌钙蛋白I在诊断急性心肌梗死患者中的价值研究

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目的 分析急性心肌梗死(acute myocardial infarction,AMI)诊断中B型钠尿肽(brain natriuretic peptide,BNP)联合心肌肌钙蛋白I(cardiac troponin I,cTnI)检验的价值.方法 非随机选取聊城市妇幼保健院于2023年1-12月确诊的50例AMI患者(B组),纳入50名同期健康体检者(A组).对比两组BNP和cTnI水平以及BNP和cTnI单一检测和联合检测诊断AMI的效能.结果 B组BNP、cTnI水平高于A组,差异有统计学意义(P均<0.05).BNP联合cTnI检测的敏感度为 90.00%(45/50)、特异度为 92.00%(46/50、准确度为 91.00%(91/100)高于cTnI检测单一检测的84.00%(42/50)、88.00%(44/50)、86.00%(86/100)及BNP单一检测的54.00%(27/50)、62.00%(31/50)、58.00%(58/100).结论 BNP联合cTnI检测的AMI诊断效能高于单一检测,具有较高的诊断价值.
Study on the Value of B-type Natriuretic Peptide Combined with Cardiac Troponin I in the Diagnosis of Patients with Acute Myocardial Infarction
Objective To analyze the value of brain natriuretic peptide(BNP)combined with cardiac troponin I(cTnI)in the diagnosis of acute myocardial infarction(AMI).Methods Fifty patients with AMI diagnosed in Liaocheng Mater-nal and Child Health Hospital from January to December 2023(group B)were non-randomly selected,and fifty healthy subjects(group A)were included in the same period.The levels of BNP and cTnI and the diagnostic efficacy of single and combined detection of BNP and cTnI in AMI were compared between the two groups.Results The levels of BNP and cTnI in group B were higher than those in group A,and the differences were statistically significant(both P<0.05).The sensitivity,specificity and accuracy of BNP combined with cTnI were 90.00%(45/50),92.00%(46/50)and 91.00%(91/100),respectively,which were higher than those of cTnI alone 84.00%(42/50),88.00%(44/50),86.00%(86/100)and BNP alone 54.00%(27/50),62.00%(31/50),58.00%(58/100).Conclusion The diagnostic effi-ciency of BNP combined with cTnI test for AMI is higher than that of single diagnosis,and it has high diagnostic value.

Brain natriuretic peptideCardiac troponin IAcute myocardial infarctionJoint inspectionDiagnostic efficiency

李凯、梁淑杰、杨帆

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聊城市妇幼保健院检验科,山东 聊城 252000

聊城市妇幼保健院新生儿疾病筛查中心,山东 聊城 252000

B型钠尿肽 心肌肌钙蛋白I 急性心肌梗死 联合检验 诊断效能

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(22)