首页|次氯酸冲洗液预防经尿道前列腺电切术后感染的临床研究

次氯酸冲洗液预防经尿道前列腺电切术后感染的临床研究

扫码查看
目的 探讨应用次氯酸冲洗液预防经尿道前列腺电切术后感染的效果.方法 回顾性选取2022年1月—2024年2月徐州医科大学第二附属医院收治的100例行尿道前列腺电切术患者的临床资料,按使用冲洗液的不同分为两组,每组50例,观察组术中应用0.000 1%次氯酸冲洗液冲洗,对照组术中应用生理盐水冲洗.对比两组患者C反应蛋白、白细胞计数、中性粒细胞比值及术后全身炎症反应综合征(systemic inflamma-tory response syndrome,SIRS)发生率.结果 术后24 h,观察组C反应蛋白、白细胞计数、中性粒细胞比值低于对照组,差异有统计学意义(P均<0.05).观察组术后SIRS发生率为4.00%(2/50),低于对照组的18.00%(9/50),差异有统计学意义(χ2=5.005,P<0.05).结论 尿道前列腺电切术中应用次氯酸冲洗液冲洗,可以降低患者术后早期炎症因子及细胞因子的升高幅度,降低术后SIRS发生率,对术后感染预防作用效果好.
Clinical Study on the Preventive Effect of Hypochlorous Acid Flushing So-lution on Postoperative Infection after Transurethral Resection of the Pros-tate
Objective To investigate the efficacy of applying hypochlorite flushing solution to prevent infection after transurethral electrolysis of the prostate.Methods The clinical data of 100 cases of patients with urethro-prostate electrocision admitted to The Second Affiliated Hospital of Xuzhou Medical University from January 2022 to February 2024 were retrospectively selected.They were divided into two groups of 50 cases each according to the different flush-ing solutions used,with 0.000 1%hypochlorite flushing solution applied intraoperatively in the observation group and saline flushing applied intraoperatively in the control group.C-reactive protein,white blood cell count,neutrophil ra-tio and the incidence of systemic inflammatory response syndrome(SIRS)in the postoperative period were compared between the two groups.Results At 24 h postoperatively,C-reactive protein,leukocyte count,and neutrophil ratio were lower in the observation group than in the control group,and the differences were statistically significant(all P<0.05).The incidence of postoperative SIRS in the observation group was 4.00%(2/50),which was lower than 18.00%(9/50)in the control group,and the difference was statistically significant(χ2=5.005,P<0.05).Conclusion The appli-cation of hypochlorite rinse solution rinsing during urethro-prostate electrocision can reduce the increase of inflamma-tory factor and cytokine in patients in the early postoperative period,reduce the incidence of postoperative SIRS,and have a good effect on the preventive effect of postoperative infection.

Hypochloric acid rinse solutionTransurethral resection of the prostateC-reactive proteinSystemic inflammatory response syndrome

宋先初、刘明勋、蒋智

展开 >

徐州医科大学第二附属医院,江苏 徐州 221000

次氯酸冲洗液 经尿道前列腺电切 C反应蛋白 全身炎症反应综合征

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(22)