The Application Value of Cytology and Tumor Marker Examination in the Diagnosis of Malignant Tumor Serous Cavity Effusion
Objective To explore the application value of exfoliative cytology and tumor marker detection in the diag-nosis of serous effusion caused by malignant tumors.Methods 280 patients with serous cavity effusion suspected of malignant tumors admitted to the Department of Medical Laboratory of Weishan County People's Hospital from Janu-ary 2023 to December 2023 were non-randomly selected as study objects.Based on the pathological diagnosis results as the gold standard,the diagnostic efficacy of exhalation cytology and tumor marker detection of serosal effusion was analyzed,and the diagnostic value was evaluated by consistency analysis of kappa values.Results 95 patients with ma-lignant tumors were confirmed by pathological examination,and 185 cases were negative.Consistency analysis showed that the combined application of serous cavity effusion exfoliative cytology and tumor marker detection had a high con-sistency with pathological examination results(Kappa=0.976).The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of combined diagnosis were higher than those of exfoliative cytology or tumor markers alone,and the differences were statistically significant(all P<0.05).Conclusion In the diagnosis of serous ef-fusion caused by malignant tumors,both exfoliative cytology and tumor marker detection show certain application value,and the combined use of the two can enhance the accuracy of diagnosis.
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