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经颅磁刺激治疗难治性三叉神经痛的可行性与效果评估

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目的 探究经颅磁刺激治疗难治性三叉神经痛的可行性与治疗效果.方法 非随机选取2022年2月—2023年2月湖南师范大学附属第一医院收治的90例难治性三叉神经痛患者为研究对象,按照治疗方法不同分为两组,各 45例.对照组采用星状神经节阻滞(stellate ganglion block,SGB)疗法,观察组在对照组的基础上采用重复经颅磁刺激治疗,对比两组疼痛程度、疼痛缓解率、疼痛全面评估评分、不良反应发生情况.结果 治疗 2周后,两组疼痛评分比较,差异无统计学意义(P>0.05).治疗 4周后、治疗 3个月后、治疗6个月后,观察组疼痛程度均低于对照组,差异有统计学意义(P均<0.05).观察组疼痛缓解率为 93.33%(42/45),优于对照组的 75.56%(34/45),差异有统计学意义(χ 2=5.414,P<0.05).治疗后,两组患者生活质量评分均升高,观察组高于对照组,差异有统计学意义(P均<0.05).观察组不良反应发生率为4.44%(2/45),低于对照组的26.67%(12/45),差异有统计学意义(χ2=8.459,P<0.05).结论 经颅磁刺激治疗难治性三叉神经痛的效果显著,不仅减轻患者疼痛、提升生活质量,同时提高疼痛缓解率,降低不良反应发生率.
Feasibility and Effect Evaluation of Transcranial Magnetic Stimulation in the Treatment of Refractory Trigeminal Neuralgia
Objective To explore the feasibility and therapeutic effect of transcranial magnetic stimulation in the treatment of refractory trigeminal neuralgia.Methods A total of ninety patients with refractory trigeminal neuralgia admitted to the First Affiliated Hospital of Hunan Normal University from February 2022 to February 2023 were non-randomly selected as the research objects.According to different treatment methods,they were divided into two groups,forty-five cases in each group.The control group was treated with stellate ganglion block(SGB)therapy,and the observation group was treated with repetitive transcranial magnetic stimulation on the basis of the control group.The pain degree,pain relief rate,comprehensive pain assessment score and adverse reactions were compared be-tween the two groups.Results After 2 weeks of treatment,there were no statistically significant differences in pain scores between the two groups(P>0.05).After 4 weeks of treatment,3 months after treatment,6 months after treat-ment,the pain degree of the observation group was lower than that of the control group,and the differences were sta-tistically significant(all P<0.05).The pain relief rate of the observation group was 93.33%(42/45),which was better than 75.56%(34/45)of the control group,and the difference was statistically significant(χ2=5.414,P<0.05).After treatment,the quality of life scores of the two groups increased,and the observation group was higher than the con-trol group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 4.44%(2/45),which was lower than 26.67%(12/45)in the control group,and the difference was statisti-cally significant(χ2=8.459,P<0.05).Conclusion Transcranial magnetic stimulation is effective in the treatment of refractory trigeminal neuralgia,which not only reduces the pain of patients,improves the quality of life,but also im-proves the pain relief rate and reduces the incidence of adverse reactions.

Cranial magnetic stimulationRefractoryTrigeminal neuralgiaStellar ganglion blockAnesthesia

余珊子、赵雨帆

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湖南师范大学附属第一医院(湖南省人民医院)麻醉科,湖南 长沙 410005

颅磁刺激 难治性 三叉神经痛 星状神经节阻滞 麻醉

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(22)