首页|铝镁匹林+氢氯吡格雷用药方案在急性缺血性脑卒中治疗中的临床价值

铝镁匹林+氢氯吡格雷用药方案在急性缺血性脑卒中治疗中的临床价值

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目的 探讨对急性缺血性脑卒中患者应用铝镁匹林+氢氯吡格雷用药方案展开治疗的临床价值.方法 非随机选取2021年5月—2024年5月高州市人民医院收治的60例急性缺血性脑卒中患者作为研究对象;以不同治疗方法分为两组,各30例.参照组使用氢氯吡格雷治疗,研究组在参照组基础上使用铝镁匹林治疗.对比两组患者治疗总有效率、美国国立卫生研究院卒中量表评分、丙二醛、超氧化物歧化酶、异构前列腺素水平.结果 研究组治疗总有效率为96.67%(29/30),高于参照组的73.33%(22/30),差异有统计学意义(χ2=6.405,P<0.05).治疗后,研究组美国国立卫生研究院卒中量表评分低于参照组,差异有统计学意义(P<0.05).治疗后,研究组的丙二醛、超氧化物歧化酶、异构前列腺素水平均优于参照组,差异有统计学意义(P均<0.05).结论 急性缺血性脑卒中患者应用铝镁匹林+氢氯吡格雷用药方案治疗可明显提升患者的治疗效果,改善患者的神经功能、脂质过氧化水平以及氧化应激反应水平.
Clinical Value of Aluminum Magnesium Aspirin+Hydroclopidogrel Regi-men in the Treatment of Acute Ischemic Stroke
Objective To explore the clinical value of the treatment of acute ischemic stroke patients with aluminum magnesium aspirin+hydroclopidogrel.Methods A total of sixty patients with acute ischemic stroke admitted to Gao-zhou People's Hospital from May 2021 to May 2024 were non-randomly selected as the study subjects.According to different treatment methods,they were divided into two groups,thirty cases in each group.The reference group was treated with hydroclopidogrel,and the study group was treated with aluminum magnesium aspirin on the basis of the reference group.The total effective rate of treatment,National Institutes of Health Stroke Scale score,malondialde-hyde,superoxide dismutase and isoprostane levels were compared between the two groups.Results The total effective rate of treatment in the study group was 96.67%(29/30),which was higher than 73.33%(22/30)in the reference group,and the difference was statistically significant(χ2=6.405,P<0.05).After treatment,the National Institutes of Health Stroke Scale score of the study group was lower than that of the reference group,and the difference was statisti-cally significant(P<0.05).After treatment,the levels of malondialdehyde,superoxide dismutase and isoprostane in the study group were better than those in the reference group,and the differences were statistically significant(all P<0.05).Conclusion The treatment of acute ischemic stroke patients with aluminum magnesium aspirin+hydroclopido-grel regimen can significantly improve the treatment effect of patients,improve the neurological function,lipid peroxi-dation and oxidative stress response of patients.

HydroclopidogrelAluminum magnesium pirinAcute ischemic strokeApplication effect

曾泓滔

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高州市人民医院急诊科,广东 高州 525200

氢氯吡格雷 铝镁匹林 急性缺血性脑卒中 应用效果

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(22)