Evaluation of the Therapeutic Effect of Tirofiban Hydrochloride on Coro-nary Atherosclerotic Heart Disease
Objective To investigate the effect of tirofiban hydrochloride in the treatment of coronary atherosclerotic heart disease(CHD).Methods A total of 120 patients with CHD admitted to the Yancheng First People's Hospital from November 2021 to November 2023 were non-randomly selected as the study objects and divided into two groups according to treatment methods,with 60 cases in each group.All patients received coronary interventional therapy,the control group received conventional anticoagulant therapy after surgery,and the study group received Tirofiban hydro-chloride.The efficacy,adverse reactions,cardiac function and vascular endothelial function of the two groups were compared.Results The total effective rate of the study group was 96.67%(58/60),higher than 86.67%(52/60)of the control group,the difference was statistically significant(χ2=3.927,P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).The levels of serum inflammatory factors in the study group were better than those in the control group,and the cardiac function and vascular endothelial function were bet-ter than those in the control group,the differences were statistically significant(all P<0.05).Conclusion Basic therapy combined with Tirofiban hydrochloride has excellent overall effect in the treatment of coronary heart disease,which can relieve chest asphyxia and chest pain,reduce the level of inflammation and improve heart function.
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