首页|莫西沙星和左氧氟沙星治疗慢性阻塞性肺疾病疗效及安全性的对比研究

莫西沙星和左氧氟沙星治疗慢性阻塞性肺疾病疗效及安全性的对比研究

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目的 研究莫西沙星和左氧氟沙星治疗慢性阻塞性肺疾病的价值.方法 非随机选取江苏省句容市人民医院于2022年1月—2023年12月收治的165例慢性阻塞性肺疾病患者为研究对象,根据治疗方式不同分为研究组(83例)和对照组(82例).研究组使用盐酸莫西沙星氯化钠,对照组使用左氧氟沙星注射液,对比两组临床疗效、肺功能、不良反应.结果 研究组治疗总有效率为98.79%(82/83),高于对照组的90.24%(74/82),差异有统计学意义(χ2=5.669,P<0.05).研究组肺功能指标均优于对照组,差异有统计学意义(P均<0.05).研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05).结论 采用莫西沙星治疗慢性阻塞性肺疾病,临床疗效较好,能够增强肺功能,且不良反应较低.
Comparative Study on the Efficacy and Safety of Moxifloxacin and Levo-floxacin in the Treatment of Chronic Obstructive Pulmonary Disease
Objective To study the value of moxifloxacin and levofloxacin in the treatment of chronic obstructive pul-monary disease.Methods A total of 165 patients with chronic obstructive pulmonary disease admitted to Jurong People's Hospital of Jiangsu Province from January 2022 to December 2023 were non-randomly selected as the re-search objects.According to different treatment methods,they were divided into the study group(83 cases)and the control group(82 cases).Moxifloxacin hydrochloride sodium chloride was used in the study group,and levofloxacin injection was used in the control group.The clinical efficacy,lung function and adverse reactions were compared be-tween the two groups.Results The effective rate of the study group was 98.79%(82/83),which was higher than 90.24%(74/82)of the control group,the difference was statistically significant(χ2=5.669,P<0.05).The lung func-tion indexes of the study group were better than those of the control group,and the differences were statistically sig-nificant(all P<0.05).The incidence of adverse reactions in study group was lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion Treatment with moxifloxacin in chrnic obstructve pul-mary diseae has good clinical efficacy,enhanced lung function,and low adverse effects.

MoxifloxacinLevofloxacinChroic obstrctive pulmnary disaseEfficacyPulmonary functionAdverse effects

张超、王文佳、王莹

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江苏省句容市人民医院呼吸科,江苏 句容 212400

江苏省句容市人民医院内分泌科,江苏 句容 212400

莫西沙星 左氧氟沙星 慢性阻塞性肺疾病 疗效 肺功能 不良反应

2024

系统医学

系统医学

ISSN:
年,卷(期):2024.9(22)