Efficacy Evaluation of Quadruple Therapy Combined with Probiotics in the Treatment of Elderly Chronic Gastritis with Helicobacter Pylori Infec-tion
Objective To explore the effect of quadruple therapy combined with probiotics on elderly patients with chronic gastritis accompanied by helicobacter pylori(Hp)infection.Methods A total of 108 elderly patients with chronic gastritis accompanied by Hp infection who were treated in Boao Yiling Life Care Center from April 2023 to April 2024 were non-randomly selected as the study objects.According to different treatment methods,the patients were divided into reference group(quadruple therapy)and observation group(quadruple therapy combined with probi-otics),with 54 cases in each group.Hp clearance rate,therapeutic effect and occurrence of adverse reactions were compared between the two groups.Results The Hp clearance rate in the observation group was 98.15%(53/54),higher than 85.19%(46/54)in the reference group,and the difference was statistically significant(χ2=5.939,P<0.05).The total effective rate of the observation group was higher than that of the reference group,and the incidence of ad-verse reactions was lower than that of the reference group,the differences were statistically significant(both P<0.05).Conclusion The combination therapy of quadruple therapy and probiotics is effective in treating elderly patients with chronic gastritis and Helicobacter pylori infection.It can effectively clear Hp in patients and improve treatment effec-tiveness,with higher safety and clinical application value.It is a feasible reference.
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