Efficacy Analysis of Linezolid Combined with Cycloserine Capsule in Pa-tients with Pulmonary Tuberculosis
Objective To analyze the effect of linezolid in combination with cycloserine capsules in the treatment of pulmonary tuberculosis.Methods Sixty cases of pulmonary tuberculosis patients admitted to Changchun Infectious Diseases Hospital from January to December 2023 were non-randomly selected as the study subjects,and were di-vided into two groups according to the difference of therapeutic drugs,with thirty cases in each group.The control group was treated with linezolid,and the observation group was treated with linezolid combined with cycloserine cap-sule.Compared the levels of lung function,immune function indexes and symptom improvement time of the two groups.Results After treatment,the lung function of the observation group were better than that of the control group,and the levels of immune function indexes of the observation group were better than those of the control group,and the differences were statistically significant(all P<0.05).The time of lesion absorption and shrinkage in the observation group was(38.21±3.12)d,the time of cavity closure was(96.31±8.41)d,and the time of sputum culture turning nega-tive was(43.21±5.12)d,which were shorter than(46.71±3.11)d,(155.24±7.14)d,and(62.31±5.11)d in the control group,and the differences were statistically significant(t=10.568,29.258,14.429,all P<0.05).Conclusion Linezolid combined with cycloserine capsules in the treatment of pulmonary tuberculosis can improve the patient's immune function,lung function,and accelerate symptom subsidence.
LinezolidCycloserineTuberculosisImmune functionPulmonary functionSymptom improvement time
NETL
NSTL
万方数据
