Preparation and Properties of Functional Bacterial Cellulose Nanocrystalline Polyurethane Composite Antibacterial Coating for Medical Purposes
The infection of medical implants is one of the difficult problems in clinical treatment.Therefore,it is crucial to conduct research on medical coatings that exhibit long-term stable antibacterial effects.In this study,oxidized modified bacterial cellulose nanocrystals were prepared using the comminution-oxidation method,and a cationic compound called biguanide was chemically grafted onto them to create a new nanometer-sized antibacterial material known as NBC-BG.By combining NBC-BG with polyurethane(PU),a medical antibacterial coating named PU-NBC-BG was developed.The structural properties of these coatings with varying proportions were investigated through various material characterization techniques.Furthermore,the antibacterial experiment demonstrated that the PU-NBC-BG coating exhibits excellent and enduring antibacterial properties as well as an effective anti-biofilm effect,making it highly promising for application in the field of medical devices.
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