Relationship Between Coronary Heart Disease and Intestinal Flora Dysregulation and the Mechanism of Targeted Intervention
In recent years,the morbidity of coronary atherosclerotic heart disease(CHD)has been trending towards youthfulness year by year,which seriously affects the life and health of Chinese residents.Previously,age,hypertension,hyperlipidaemia and other risk factors for the development of CHD were considered.In recent years,a number of clinical studies and animal model studies have confirmed that intestinal flora dysregulation,intermediate metabolites of flora and the occurrence and development of CHD have a close association,suggesting that regulating the balance of intestinal flora may be a new strategy for the prevention and treatment of CHD.This article reviews the relationship between CHD and intestinal flora dysregulation,and summarises the mechanism of targeting intestinal flora and its metabolites for the treatment of CHD,with a view to guiding the clinical prevention and treatment of CHD.
万方数据
维普
