Metabolites of Intestinal Flora and Vascular Endothelial Function
Vascular endothelial function is critical for maintaining homeostasis of the cardiovascular system,and its dysfunction is an important cause of cardiovascular disease.In recent years,many studies have shown that intestinal flora are involved in the alteration of vascular endothelial function,which may affect vascular endothelial function by directly influencing intestinal flora or indirectly influencing intestinal flora metabolites,such as short-chain fatty acids,secondary bile acids,indole-3-carboxaldehyde,trimethylamine-N-oxides,phenylacetylglutamine,lipopolysaccharides,and uremic toxins.The metabolites of intestinal flora discovered in recent years are reviewed to provide a theoretical basis and new ideas for exploring the effects of intestinal flora on vascular endothelial function.
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