Monogenic hypertension is an important genetic pattern of hypertension,which is caused by a single genetic variant that follows Mendelian inheritance.At present,the clinical incidence and pathogenesis of monogenic hypertension are not completely clear,and it is difficult to identify and diagnose clinically.The purpose of this paper is to systematically elaborate the classification,mutated genes,mechanism characteristics,diagnosis and treatment of monogenic hypertension,in order to provide more references for the clinical diagnosis and treatment of this disease in the future.
关键词
单基因高血压/孟德尔遗传/基因检测
Key words
Monogenic hypertension/Mendelian inheritance/Gene test