肾动脉狭窄介入治疗中的血流动力学评估进展
Hemodynamic Evaluation in Interventional Therapy of Renal Artery Stenosis
常羽茜 1李昱熙 1刘旭 1刘志浩 1张岩1
作者信息
- 1. 北京大学第一医院心内科,北京 100034
- 折叠
摘要
肾动脉狭窄是导致继发性高血压及肾功能不全的常见原因,介入治疗是重要的治疗方法之一.既往大规模随机对照研究表明,介入治疗相比单纯药物治疗可能无法为动脉粥样硬化性肾动脉狭窄患者带来获益,但这些研究存在选择偏倚等缺陷,其结论引发了广泛争议.现主要探究肾动脉狭窄的血流动力学评估方法,总结血流动力学指导的介入治疗对患者预后的预测能力,并对血流动力学评估下介入治疗在肾动脉狭窄患者中的应用及发展作出展望.
Abstract
Renal artery stenosis is a common cause of secondary hypertension and renal insufficiency,and interventional therapy is one of the important treatment methods.Previous large-scale randomized controlled trials have shown that interventional therapy may not bring benefit for patients with atherosclerotic renal artery stenosis compared to drug therapy alone,but the conclusion has caused wide debate due to the shortcomings in these studies such as selection bias.This article mainly explores the hemodynamic evaluation methods of renal artery stenosis,summarizes the ability of hemodynamic guided interventional therapy to predict the prognosis of patients,and makes prospects for the application and development of interventional therapy under hemodynamic evaluation in patients with renal artery stenosis.
关键词
肾动脉狭窄/介入治疗/血流动力学/肾脏血流储备分数Key words
Renal artery stenosis/Interventional therapy/Hemodynamics/Renal fractional flow reserve引用本文复制引用
基金项目
中央高水平医院临床科研业务费资助(北京大学第一医院高质量临床研究专项)(2022CR77)
中央高水平医院临床科研业务费资助(北京大学第一医院科技成果转化孵育引导基金项目)(2022CX07)
出版年
2024
NETL
NSTL
万方数据