The Relationship Between Endoplasmic Reticulum Stress and Endothelial Dysfunction and Its Clinical Treatment
As an early critical event in atherosclerosis(AS),endothelial dysfunction runs throughout the AS process and is closely related to the pathogenesis of many other cardiovascular diseases.It has been found that the expression of endoplasmic reticulum stress(ERS)-related proteins is increasing in cardiovascular disease,and ERS may exacerbate the progression of cardiovascular disease by promoting endothelial dysfunction.ERS may aggravate the progression of cardiovascular disease by promoting endothelial dysfunction.This article summarizes the research progress of the relationship between ERS and endothelial dysfunction and AS,and introduces some drugs to alleviate ERS,which is expected to provide certain reference value for the clinical treatment of endothelial dysfunction and cardiovascular diseases.
Endoplasmic reticulum stressUnfolded protein responseEndothelial dysfunctionAtherosclerosis
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