Drug Regulated mTOR Related Signaling Pathways In Ischemic Heart Disease
Ischemic heart disease is a prominent global cause of mortality.The mammalian target of rapamycin(mTOR)is a serine/threonine protein kinase that regulates protein synthesis,cell growth,proliferation,and autophagy.Recent research has substantiated the significant role played by mTOR in the pathogenesis and progression of ischemic heart disease.This article provides an overview of the advancements made in understanding mTOR and its associated signaling pathways in relation to ischemic heart disease,aiming to offer novel insights for clinical treatment strategies and drug development.
Mammalian target of rapamycinIschemic heart diseaseIschemia reperfusionIschemic heart failureCardiac remodeling
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维普
