Interaction of Interleukin-13 and Immunocyte in Cardiovascular Disease
Interleukin(IL)-13 is a member of Th2 cytokine family,which has important immunomodulatory activities and interacts with a variety of immunocytes.In recent years,the relationship between IL-13 and myocardial injury has attracted attention.Myocardial injury is manifested as ischemia,hypoxia,injury and necrosis of myocardial cells,and eventually lead to myocardial dysfunction,which can be caused by a variety of diseases,such as coronary heart disease,heart failure,myocarditis and so on.This article reviews the interaction between IL-13 and immunocyte such as monocyte-macrophages,T lymphocytes,and eosinophils in the mechanism of myocardial injury.
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