Chimeric antigen receptor T(CAR-T)cell therapy is currently the hottest research field in cellular immunotherapy,and has made brilliant achievements in tumor treatment.With the deepening of research,CAR-T cell therapy has also made a major breakthrough in non-tumor diseases.CAR-T cells,a type of adoptive T cell,combine the antigen-binding properties of antibodies with the effector function of T cells to target the elimination of specific cells.For myocardial fibrosis which there is no effective treatment,CAR-T cell therapy may be a new treatment idea and direction.This article reviews the current research progress of CAR-T cell therapy in myocardial fibrosis.
关键词
嵌合抗原受体T细胞治疗/细胞免疫治疗/心肌纤维化
Key words
Chimeric antigen receptor T cell therapy/Cellular immunotherapy/Myocardial fibrosis
维普
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