Application of Single Cell Sequencing in Myocardial Infarction
In recent years,myocardial infarction(MI)caused by advanced atherosclerosis in cardiovascular diseases has become one of the major causes of death worldwide.Due to the high heterogeneity of its cells in MI,there has been no effective targeted therapy strategy in the clinical stage.Single cell sequencing technology,which aims to reveal the gene structure and expression status of individual cells,is rapidly developing in various fields and is gradually gaining attention in clinical research of MI.This article reviews the single cell sequencing methods of MI,and discusses the heterogeneity of MI cells,potential therapeutic targets,and the prognostic mechanism of cardiac remodeling,which is expected to provide a basis for precise and targeted treatment.
Single cell sequencingMyocardial infarctionHeterogeneityPrecision medicine
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