Numerous evidence shows that Rho/ROCK pathway regulates cell growth,development,migration,proliferation and death to varying degrees,and plays an important role in various diseases.In addition,the interaction of Rho/ROCK pathway with fibroblasts,calcium ions and inflammatory factors has an important impact on the occurrence and development of pulmonary hypertension and cardiovascular diseases.In recent years,the role of Rho/ROCK pathway in arrhythmia has attracted much attention,and relevant studies are summarized to provide further research reference for antiarrhythmic drugs.
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