Application of Cardiac Magnetic Resonance in Prognosis and Risk Stratification in Light-Chain Amyloidosis
Light-chain amyloidosis is a systemic disease,caused by tissue deposition of insoluble amyloid fibrils made up of immunoglobulin light chain that leads to organ dysfunction.Cardiac involvement is a key determinant of patient survival.Therefore,accurate assessment of the degree of cardiac involvement is essential for the prognosis and risk stratification of patients with light-chain amyloidosis.Different cardiac magnetic resonance imaging techniques such as cine imaging,perfusion imaging,late gadolinium enhancement and T1 mapping can assess the degree of cardiac involvement from in various aspects,which can provide important value for prognosis and risk stratification in patients with light-chain amyloidosis.In this article,we review the application of cardiac magnetic resonance in the prognosis and risk stratification of patients with light-chain amyloidosis.
Light-chain amyloidosisCardiac magnetic resonanceMagnetic resonance imagingPrognosisRisk stratification
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