心脏磁共振在轻链型淀粉样变预后评估及风险分层中的研究进展
Application of Cardiac Magnetic Resonance in Prognosis and Risk Stratification in Light-Chain Amyloidosis
王银秋 1彭礼清1
作者信息
- 1. 四川大学华西医院放射科,四川成都 610041
- 折叠
摘要
轻链型淀粉样变是一种由免疫球蛋白轻链聚集形成的淀粉样原纤维在组织及器官中沉积并引起组织器官损伤的系统性疾病,心脏受累是患者预后的决定性因素.因此,心脏受累程度的准确评估对于轻链型淀粉样变患者的预后评估及风险分层至关重要.电影成像、灌注成像、延迟强化、T1 mapping等不同心脏磁共振成像技术可以从多个方面评估轻链型淀粉样变患者的心脏受累程度,为患者预后评估及风险分层提供重要价值.现就心脏磁共振在轻链型淀粉样变患者的预后评估及风险分层中的研究进展予以综述.
Abstract
Light-chain amyloidosis is a systemic disease,caused by tissue deposition of insoluble amyloid fibrils made up of immunoglobulin light chain that leads to organ dysfunction.Cardiac involvement is a key determinant of patient survival.Therefore,accurate assessment of the degree of cardiac involvement is essential for the prognosis and risk stratification of patients with light-chain amyloidosis.Different cardiac magnetic resonance imaging techniques such as cine imaging,perfusion imaging,late gadolinium enhancement and T1 mapping can assess the degree of cardiac involvement from in various aspects,which can provide important value for prognosis and risk stratification in patients with light-chain amyloidosis.In this article,we review the application of cardiac magnetic resonance in the prognosis and risk stratification of patients with light-chain amyloidosis.
关键词
轻链型淀粉样变/心脏磁共振/磁共振成像/预后/风险分层Key words
Light-chain amyloidosis/Cardiac magnetic resonance/Magnetic resonance imaging/Prognosis/Risk stratification引用本文复制引用
基金项目
四川省科技厅重点研发项目(2021YFS0142)
出版年
2024
NETL
NSTL
万方数据