Programmed Cell Death of Vascular Smooth Muscle Cell in Aortic Dissection
Aortic dissection(AD),with severe pain in the chest and back as its main clinical manifestation,is a cardiovascular disease characterized by critical condition,rapid development,and high mortality,seriously affecting patients'life safety.Currently,research on the pathogenesis of AD focuses on inflammatory response,oxidative stress,genetic factors,and so on.In recent years,it has been found that vascular smooth muscle cell death is closely related to the occurrence of AD.Therefore,this study will take vascular smooth muscle cell programmed cell death as the starting point,summarize the currently known types of vascular smooth muscle cell programmed cell death,inducing factors,and their roles and mechanisms of occurrence in AD,with the aim of exploring the potential value of preventing and treating AD by inhibiting vascular smooth muscle cell programmed death in the future.
Aortic dissectionVascular smooth muscle cellProgrammed cell death