The Relationship Between Cardiac Myosin-Binding Protein-C Phosphorylation and Chronic Heart Failure
Cardiac myosin-binding protein-C is an essential component of the thick filaments in the myocardium.Its phosphorylation levels can affect the contraction and relaxation function of the myocardium.Given the change of its phosphorylation level is closely related to the occurrence and development of chronic heart failure,it has gradually become a key site in the study of chronic heart failure in recent years.This article reviews the relationship-between myosin binding protein-C phosphorylation and chronic heart failure and its potential as a therapeutic target.