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难治性高血压的认识和治疗进展

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难治性高血压是高血压的重要特殊表型之一,定义为尽管使用3种及以上抗高血压药,血压仍未达到目标值。已有大量证据表明难治性高血压人群具有较高的不良心血管事件发生率以及全因死亡率,但该特殊人群尚未在临床工作中得到广泛重视及充分管理。现就难治性高血压的定义、流行病学、相关机制及治疗进展做简要综述,以便临床医生规范管理该类人群。
Recognition and Treatment of Resistant Hypertension
Resistant hypertension is one of the important specific phenotypes of hypertension,which defined as uncontrolled blood pressure despite treatment with at least three or more antihypertensive agents.Compelling evidence has shown that such a population has a greater incidence of adverse cardiovascular events as well as mortality.However,it has not yet been widely emphasized and adequately managed in clinic.In the article,we provide a brief review on the definition,epidemiology,related mechanisms and treatment options of resistant hypertension,so that clinicians can standardize the management of this population.

Resistant hypertensionDefinitionEpidemiologyMechanismTherapeutic

姚媛媛、张鑫、叶润宇、陈晓平

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四川大学华西医院心脏内科,四川 成都 610041

难治性高血压 定义 流行病学 机制 治疗

2024

心血管病学进展
成都市心血管病研究所,成都市第三人民医院

心血管病学进展

CSTPCD
影响因子:0.932
ISSN:1004-3934
年,卷(期):2024.45(12)