Human Epididymis Protein 4 in Cardiovascular and Renal Diseases
Human epididymis protein 4(HE4)is a peptide with 2 whey acidic protein four-disculfidecore domains,consisting of 124 amino acids.It is a whey acidic protein and belongs to the family of protease inhibitors.HE4 is currently widely used in the diagnosis and prognosis assessment of gynecological diseases.In recent years,studies have shown that HE4 exhibits high levels of expression in patients with cardiovascular and renal diseases,especially playing an important role in cardiovascular diseases such as heart failure,acute coronary syndrome,cardiomyopathy,as well as chronic kidney disease.This article provides an overview of the current research status of HE4 in cardiovascular and renal diseases.
Human epididymis protein 4Heart failureAcute coronary syndromeCardiomyopathyChronic kidney disease
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